The key to successful scale-up is in the proper understanding of the critical factors that influence product performance. An effective process scale up framework will deliver a solution that is fully optimized for safety, capital/operating costs, capacity, performance and sustainability. Our approach is to integrate with our customers’ teams to understand the scientific, commercial, quality and regulatory requirements. We break each process down into recognizable engineering unit operations and analyze them to develop a strategy and framework for scale up. Our technical risk management approach to identify the data required from lab and pilot scale development studies is built into a robust process design suitable for implementation.
We carefully review the potential move from batch-based to continuous processing and then deliver the required process and operational developments. We don’t just look at the technical and organizational challenges; we analyze the potential benefits around finance, sustainability and occupational health.